Description
Introduction
Articaine is a form of an amide local anesthetic that is most commonly used in dentistry. The chemical name for articaine hydrochloride is 2-Thiophenecarboxylic acid-4-methyl-3- ((1-oxo-2-(propyl amino) propyl) amino)-methyl ester hydrochloride (C13H21ClN2O3S). The CAS Number is 23964-57-0. It is a white or almost white crystalline powder with the molecular weight of 320.84 g/mol. This drug is originally known as carticaine. It has different molecular structure with a thiophene ring instead of the usual benzene ring present in the other amide anesthetic drugs. The half-life of Articaine is 1.8 hours. Like other amide anesthetics it blocks nerve conduction when it is inflated around a nerve. The action of articaine can be prolonged by combining it with a vasoconstrictor such as adrenaline. If needed, stock solutions can be created in advanced and can be stored as aliquots in tightly sealed vials at -20°C. The Articaine is marketed as a colourless liquid in vials/cartridges (2ml in each vial/cartridge). The Articaine is available in two variants i.e. Articaine-100 & Articaine-200. Articaine-200 is more potent than Articaine-100.
The dosage can be based on type and extent of surgical procedure, depth of anesthesia, degree of muscular relaxation, and condition of the patient. For paediatric patients, dosage based on their age, weight, physical condition of the patient and extent of surgical procedure.
The global market of articaine hydrochlorides is expected to reach USD 1363.0 million by 2021, at a CAGR of 7.0% during the forecast period.
Based on application of articaine hydrochloride, , the nerve block segment is by far the fastest growing segment of global articaine hydrochloride market and it is expected to reach USD 624.8 million by 2021.
Based on end users of articaine hydrochloride, the dental clinics segment commands the largest market share of global articaine hydrochloride market and it is expected to grow at a CAGR of 7.1% during the period 2016 to 2021.
Today’s availability of a variety of local anesthetics enabled dentists to select an anesthetic which has specific properties like time of onset and its duration, hemostatic control, degree of cardiac or neurotoxic side effects that are appropriate specific dental procedures for each individual patient. Articaine with its greater ability to diffuse through tissues become a very widely used local anesthetic in the European and Canadian markets. The US market is growing steadily. Articaine is the second most used local anesthetic in the United States. In U.S. articaine share is around 40%. In Canada, Articaine hydrochloride is the number one choice of the dentists.
Articaine hydrochloride is most popular local anesthetic for dentistry in a number of European countries. Germany is the biggest buyer of Articaine hydrochloride. In Germany, 97% of the anesthetic used by dentists is articaine hydrochloride. In Italy and France articaine is most used by dentists.
In Australia, around 70% of the dentists use articaine as local anesthetic. In Asian countries, China is one of the biggest producers of Articaine hydrochloride and its products are mostly exported to Middle-East and European regions. Thus, Articaine hydrochloride is being used increasingly by the medical professional nowadays.
Key Players
The leading market players in the global articaine hydrochloride market include; 3M, Anhui BBCA Pharmaceutical Co., Ltd., Dentsply Sirona, Inibsa Dental S.L.U, Jinan Chenghui Shuangda Chemical Co., Ltd, Jinan Ruixing Pharmaceutical Technology Co., Ltd, Manus Aktteva Biopharma LLP, Pfizer Inc, Pierrel S.p.A, Sanofi, Septodont, Siegfried AG, Sigma Aldrich and many others.
Study Objectives
To provide insights about factors, influencing and affecting the market growth.
To provide historical and forecast revenue of the market segments and sub-segments with respect to regional markets and their countries.
To provide historical and forecast revenue of the market segments based on application, and end users for global articaine hydrochloride market.
To provide strategic profiling of key players in the market, comprehensively analyzing their market share, core competencies, and drawing a competitive landscape for the market.
To provide economic factors that influences the global articaine hydrochloride market.
Target Audience
Articaine hydrochloride manufacturers
Articaine API manufacturers
Articaine hydrochloride suppliers
Research Laboratories
Hospitals & Clinics
Service Suppliers
Potential Investors
Key executive (CEO and COO) and strategy growth manager
Key Findings
• The global market for articaine hydrochloride is expected to grow at a CAGR of 7.0% during the period 2016 to 2021 to reach USD 1363.0 million by 2021.
• The articaine hydrochloride market in Asia is expected to grow rapidly during 2016 to 2021 whereas Europe will remain the largest market by 2021.
• The global market for articaine hydrochloride by application, infiltration segment is expected to witness highest CAGR of 6.9% during the period 2016 to 2021.
• Based on the end users, dental clinics segment commands the largest market share of global articaine hydrochloride market; registered 7.1% share in 2015
The reports also cover country level analysis:
• North America
o US
o Canada
• Europe
o Germany
o U.K.
o Italy
o Spain
o France
o Rest of Western Europe
o Eastern Europe
• Asia-Pacific
o Japan
o China
o India
o Republic of Korea
o Rest of Asia-Pacific
1 Report Prologue 15
2 Global Scenario of Oral Health 18
2.1 Introduction 18
2.2 Burden of Disease 19
2.3 Development of Articaine Hydrochloride Industry 22
2.4 Status of Articaine Hydrochloride Industry 22
3 Scope of Study 24
3.1 Research Objective 24
3.2 Assumptions & Limitations 24
3.2.1 Assumptions 24
3.2.2 Limitations 24
3.3 Market Structure 25
4 Research Methodology 26
4.1 Primary Research 27
4.2 Secondary Research 27
5 Market Dynamics 28
5.1 Introduction 28
5.2 Drivers 28
5.2.1 Increasing Incidences of Dental Caries and Other Periodontal Diseases 28
5.2.2 Advancement in Dental Anesthesia Delivery System Device 29
5.2.3 Increasing Popularity of Articaine in Dental Industry 29
5.2.4 Vigorous Research and Development Efforts 29
5.3 Restraints 30
5.3.1 Alternative Local Anesthesia Available in Developing Countries 30
5.4 Opportunities 30
5.5 Challenges 31
6 Market Factor Analysis 32
6.1 Value Chain Analysis 32
6.1.1 Raw Material Sourcing 32
6.1.2 Product Manufacturing 33
6.1.3 Inventory Management and Distribution 33
6.1.4 Wholesaler & Retailers 33
6.1.5 Consumers 33
6.2 Porters Five Forces Model 34
6.2.1 Bargaining Power of Suppliers 35
6.2.2 Bargaining Power of Buyers 35
6.2.3 Threat of New Entrants 35
6.2.4 Threat of Substitutes 35
6.2.5 Intensity of Rivalry 35
7 Manufacturing Technology of Articaine Hydrochloride 36
7.1 Introduction 36
7.1.1 Terminal Sterilization Process 36
7.1.2 Aseptic Manufacturing 36
8 Global Articaine Hydrochloride Market, By Application 38
8.1 Introduction 38
8.2 Infiltration 39
8.3 Nerve Block 40
9 Global Articaine Hydrochloride Market, By End User 42
9.1 Introduction 42
9.2 Dental Clinics 43
9.3 Hospitals 44
9.4 Academics & Research Institutes 45
10 Global Articaine Hydrochloride Market, By Region 47
10.1 Introduction 47
10.2 North America 49
10.2.1 The U.S. 52
10.2.1.1 Market Scenario 52
10.2.1.2 Key Participants 55
10.2.1.3 Key Market Trends and Developments 55
10.2.2 Canada 56
10.2.2.1 Market Scenario 56
10.2.2.2 Key Participants 59
10.3 Europe 60
10.3.1 Western Europe 63
10.3.1.1 Germany 65
10.3.1.1.1 Market Scenario 65
10.3.1.1.2 Key Participants 68
10.3.1.1.3 Key Developments 68
10.3.1.2 France 69
10.3.1.2.1 Market Scenario 69
10.3.1.2.2 Key Participants 71
10.3.1.3 UK 72
10.3.1.3.1 Market Scenario 72
10.3.1.3.2 Key Participants 75
10.3.1.4 Italy 76
10.3.1.4.1 Market Scenario 76
10.3.1.4.2 Key Participants 78
10.3.1.5 Spain 79
10.3.1.5.1 Market Scenario 79
10.3.1.5.2 Key Participants 81
10.3.2 Eastern Europe 82
10.4 Asia-Pacific 83
10.4.1 Australia 87
10.4.1.1 Market Scenario 87
10.4.1.2 Key Participants 89
10.4.1.3 Key Development 89
10.4.2 Japan 90
10.4.2.1 Market Scenario 90
10.4.2.2 Key Participants 92
10.4.3 China 93
10.4.3.1 Market Scenario 93
10.4.3.2 Key Participants 95
10.4.4 India 96
10.4.4.1 Market Scenario 96
10.4.4.2 Key Participants 98
10.5 Middle East & Africa 99
10.5.1 Market Scenario 99
10.5.2 Key Participants 103
10.5.3 Key Development 104
11 Global Import & Export of Articaine Hydrochloride 105
11.1 Global Articaine Hydrochloride Export Data 105
11.2 Global Articaine Hydrochloride Import Data 106
11.3 China Articaine Hydrochloride Import & Export Data 107
12 Competitive Landscape 108
12.1 Introduction 108
12.1.1 Product Development and Launch 109
12.1.2 Mergers & Acquisitions 110
12.1.3 Agreements and Expansions 110
12.1.4 FDA Approvals 110
12.1.5 Award & Recognition 111
12.1.6 Others (Licensing & Product upgrade) 111
12.2 Company Share Analysis 112
13 Company Profiles 113
13.1 3M 113
13.1.1 Company Overview 113
13.1.2 Product Overview 113
13.1.3 Financial Overview 114
13.1.4 Key Developments 115
13.1.5 SWOT Analysis 115
13.1.6 MRFR Analysis 115
13.2 Anhui BBCA Pharmaceutical Co., Ltd. 116
13.2.1 Overview 116
13.2.2 Product Overview 116
13.2.3 Financials 116
13.2.4 SWOT Analysis 117
13.2.5 MRFR Analysis 117
13.3 Dentsply Sirona 118
13.3.1 Company Overview 118
13.3.2 Product Overview 118
13.3.3 Financial Overview 119
13.3.4 Key Developments 120
13.3.5 SWOT Analysis 120
13.3.6 MRFR Analysis 121
13.4 Inibsa Dental S.L.U 122
13.4.1 Company Overview 122
13.4.2 Product Overview 122
13.4.3 Financial Overview 122
13.4.4 Key Developments 122
13.4.5 SWOT Analysis 123
13.4.6 MRFR Analysis 123
13.5 Jinan Chenghui Shuangda Chemical Co., Ltd. 124
13.5.1 Overview 124
13.5.2 Product Overview 124
13.5.3 Financials 124
13.5.4 SWOT Analysis 125
13.5.5 MRFR Analysis 125
13.6 Jinan Ruixing Pharmaceutical Technology Co., Ltd 126
13.6.1 Overview 126
13.6.2 Product Overview 126
13.6.3 Financials 126
13.6.4 SWOT Analysis 127
13.6.5 MRFR Analysis 127
13.7 Manus Aktteva Biopharma LLP 128
13.7.1 Overview 128
13.7.2 Product Overview 128
13.7.3 Financials 128
13.7.4 SWOT Analysis 129
13.7.5 MRFR Analysis 129
13.8 Pfizer Inc. 130
13.8.1 Overview 130
13.8.2 Product Overview 130
13.8.3 Financials 131
13.8.4 Key Developments 132
13.8.5 SWOT Analysis 133
13.8.6 MRFR Analysis 133
13.9 Pierrel S.p.A 134
13.9.1 Overview 134
13.9.2 Contract Manufacturing Unit 134
13.9.3 Product Overview 135
13.9.4 Financials 135
13.9.5 Key Developments 136
13.9.6 SWOT Analysis 136
13.9.7 MRFR Analysis 136
13.10 Sanofi 137
13.10.1 Company Overview 137
13.10.2 Product/Business Segment Overview 137
13.10.3 Financial Overview 138
13.10.4 Key Development 139
13.10.5 SWOT Analysis 140
13.10.6 MRFR Analysis 140
13.11 Septodont 141
13.11.1 Company Overview 141
13.11.2 Product/Business Segment Overview 141
13.11.3 Financial Overview 141
13.11.4 Key Development 141
13.11.5 SWOT Analysis 142
13.11.6 MRFR Analysis 142
13.12 Siegfried AG 143
13.12.1 Overview 143
13.12.2 Product Overview 143
13.12.3 Financial 143
13.12.4 Key Developments 144
13.12.5 SWOT Analysis 145
13.12.6 MRFR Analysis 145
13.13 Sigma Aldrich 146
13.13.1 Overview 146
13.13.2 Product Overview 146
13.13.3 Financial 147
13.13.4 SWOT Analysis 148
13.13.5 MRFR Analysis 149
14 Global Economic Impact on Articaine Hydrochloride Industry 150
14.1 Global Macroeconomic Environment Analysis 150
14.2 Global Macroeconomic Environment Development Trend 150
15 Strategies 152
15.1 Strategies And Reform Done By China For Oral Health Maintainance 152
16 Conclusion 153
17 Case Study 154
TABLE 1 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2021) (USD MILLION) 38
TABLE 2 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR INFILTRATION, BY REGION (2011-2021) (USD MILLION) 40
TABLE 3 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR NERVE BLOCK MARKET, BY REGION (2011-2021) (USD MILLION) 41
TABLE 4 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY END USER (2011-2021) (USD MILLION) 42
TABLE 5 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR DENTAL CLINICS, BY REGION (2011-2021) (USD MILLION) 43
TABLE 6 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR HOSPITALS, BY REGION (2011-2021) (USD MILLION) 44
TABLE 7 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY ACADEMIC & RESEARCH INSTITUTES,BY REGION (2011-2016) (USD MILLION) 45
TABLE 8 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY REGION, (2011-2021) (USD MILLION) 47
TABLE 9 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 48
TABLE 10 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY END USER, (2011-2021) (USD MILLION) 48
TABLE 11 NORTH AMERICA ARTICAINE HYDROCHLORIDE MARKET, BY COUNTRY, (2011-2021) (USD MILLION) 49
TABLE 12 NORTH AMERICA ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 50
TABLE 13 NORTH AMERICA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 50
TABLE 14 NORTH AMERICA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 50
TABLE 15 NORTH AMERICA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 50
TABLE 16 NORTH AMERICA ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 51
TABLE 17 NORTH AMERICA ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 51
TABLE 18 U.S. ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 53
TABLE 19 U.S. ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 53
TABLE 20 U.S. ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 53
TABLE 21 U.S. ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 54
TABLE 22 U.S. ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 54
TABLE 23 U.S. ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 54
TABLE 24 CANADA ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 57
TABLE 25 CANADA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 57
TABLE 26 CANADA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 57
TABLE 27 CANADA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 58
TABLE 28 CANADA ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 58
TABLE 29 CANADA ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 58
TABLE 30 EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY COUNTRY, (2011-2021) (USD MILLION) 61
TABLE 31 EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 61
TABLE 32 EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 61
TABLE 33 EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 62
TABLE 34 EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 62
TABLE 35 EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 62
TABLE 36 EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 63
TABLE 37 WESTERN EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 63
TABLE 38 WESTERN EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 64
TABLE 39 GERMANY ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 66
TABLE 40 GERMANY ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 66
TABLE 41 GERMANY ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 67
TABLE 42 GERMANY ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 67
TABLE 43 GERMANY ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 67
TABLE 44 GERMANY ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 68
TABLE 45 FRANCE ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 70
TABLE 46 FRANCE ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 70
TABLE 47 FRANCE ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 70
TABLE 48 FRANCE ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 70
TABLE 49 FRANCE ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 71
TABLE 50 FRANCE ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 71
TABLE 51 UK ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 73
TABLE 52 UK ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 73
TABLE 53 UK ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 73
TABLE 54 UK ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 74
TABLE 55 UK ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 74
TABLE 56 UK ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 74
TABLE 57 ITALY ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 76
TABLE 58 ITALY ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 76
TABLE 59 ITALY ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 76
TABLE 60 ITALY ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 77
TABLE 61 ITALY ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 77
TABLE 62 ITALY ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 77
TABLE 63 SPAIN ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 79
TABLE 64 SPAIN ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 79
TABLE 65 SPAIN ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES), (2011-2021) 79
TABLE 66 SPAIN ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) 80
TABLE 67 SPAIN ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 80
TABLE 68 SPAIN ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 80
TABLE 69 EASTERN EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION, (2011-2021) (USD MILLION) 82
TABLE 70 EASTERN EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY END-USER, (2011-2021) (USD MILLION) 82
TABLE 71 ASIA PACIFIC ARTICAINE HYDROCHLORIDE MARKET, BY COUNTRY (2011-2016) (USD MILLION) 84
TABLE 72 ASIA-PACIFIC ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) 84
TABLE 73 ASIA-PACIFIC ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES), (2011-2021) 84
TABLE 74 ASIA-PACIFIC ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES) (2011-2021) 85
TABLE 75 ASIA-PACIFIC ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) (2011-2021) 85
TABLE 76 ASIA-PACIFIC ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2021) (USD MILLION) 85
TABLE 77 ASIA-PACIFIC ARTICAINE HYDROCHLORIDE MARKET, BY END-USER (2011-2021) (USD MILLION) 86
TABLE 78 AUSTRALIA ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) (2011-2021) 87
TABLE 79 AUSTRALIA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES) (2011-2021) 88
TABLE 80 AUSTRALIA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES) (2011-2021) 88
TABLE 81 AUSTRALIA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) (2011-2021) 88
TABLE 82 AUSTRALIA ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2016) (USD MILLION) 89
TABLE 83 AUSTRALIA ARTICAINE HYDROCHLORIDE MARKET, BY END-USER (2011-2016) (USD MILLION) 89
TABLE 84 JAPAN ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) (2011-2021) 90
TABLE 85 JAPAN ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES) (2011-2021) 90
TABLE 86 JAPAN ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES) (2011-2021) 91
TABLE 87 JAPAN ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) (2011-2021) 91
TABLE 88 JAPAN ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2016) (USD MILLION) 91
TABLE 89 JAPAN ARTICAINE HYDROCHLORIDE MARKET, BY END-USER (2011-2016) (USD MILLION) 92
TABLE 90 CHINA ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) (2011-2021) 93
TABLE 91 CHINA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES) (2011-2021) 93
TABLE 92 CHINA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES) (2011-2021) 94
TABLE 93 CHINA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) (2011-2021) 94
TABLE 94 CHINA ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2016) (USD MILLION) 94
TABLE 95 CHINA ARTICAINE HYDROCHLORIDE MARKET, BY END-USER (2011-2016) (USD MILLION) 95
TABLE 96 INDIA ARTICAINE HYDROCHLORIDE MARKET, BY AVERAGE SELLING PRICE (ASP) PER BOX ($) (50 CARTRIDGES) (2011-2021) 96
TABLE 97 INDIA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF BOXES) (2011-2021) 96
TABLE 98 INDIA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (NUMBER OF CARTRIDGES) (2011-2021) 96
TABLE 99 INDIA ARTICAINE HYDROCHLORIDE MARKET, BY VOLUME (KG) (2011-2021) 97
TABLE 100 INDIA ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2016) (USD MILLION) 97
TABLE 101 INDIA ARTICAINE HYDROCHLORIDE MARKET, BY END-USER (2011-2016) (USD MILLION) 97
TABLE 102 MIDDLE EAST & AFRICA ARTICAINE HYDROCHLORIDE MARKET, BY COUNTRY (2011-2021) (USD MILLION) 100
TABLE 103 MIDDLE EAST & AFRICA ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2021) (USD MILLION) 101
TABLE 104 MIDDLE EAST & AFRICA ARTICAINE HYDROCHLORIDE MARKET, BY END-USER (2011-2021) (USD MILLION) 101
TABLE 105 MIDDLE EAST ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2021) (USD MILLION) 102
TABLE 106 MIDDLE EAST ARTICAINE HYDROCHLORIDE MARKET, BY END-USER (2011-2021) (USD MILLION) 102
TABLE 107 AFRICA ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2011-2021) (USD MILLION) 103
TABLE 108 AFRICA ARTICAINE HYDROCHLORIDE MARKET, BY END-USER (2011-2021) (USD MILLION) 103
TABLE 109 GLOBAL EXPORT OF ARTICAINE HYDROCHLORIDE, BY QUANTITY, 2011-2016 (TONS) 105
TABLE 110 GLOBAL IMPORT OF ARTICAINE HYDROCHLORIDE, BY QUANTITY, 2011-2016 (TONS) 106
TABLE 111 CHINESE IMPORT AND EXPORT OF ARTICAINE HYDROCHLORIDE, BY QUANTITY, 2011-2016 (TONS) 107
TABLE 112 3M: KEY DEVELOPMENT 115
TABLE 113 DENTSPLY SIRONA: KEY DEVELOPMENT 120
TABLE 114 INIBSA DENTAL: KEY DEVELOPMENT 122
TABLE 115 PFIZER: PRODUCT OVERVIEW 130
TABLE 116 PFIZER: KEY DEVELOPMENTS 132
TABLE 117 PIERREL S.P.A.: PRODUCT OVERVIEW 135
TABLE 118 SANOFI: KEY DEVELOPMENT 139
TABLE 119 SEPTODONT: KEY DEVELOPMENT 141
TABLE 120 SIGMA ALDRICH: PRODUCT OVERVIEW 143
TABLE 121 SIGMA ALDRICH: PRODUCT OVERVIEW 146
FIGURE 1 GLOBAL ARTICAINE HYDROCHLORIDE MARKET SHARE, BY APPLICATION 2015 (%) 16
FIGURE 2 GLOBAL ARTICAINE HYDROCHLORIDE MARKET SHARE, BY END USERS, 2015 (%) 16
FIGURE 3 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY REGION, 2015 (%) 17
FIGURE 4 SELECTED ASSOCIATIONS BETWEEN ORAL CONDITIONS AND GENERAL HEALTH 18
FIGURE 5 DISTIBUTION OF TOOTH DECAY DISORDER, BY COUNTRY 19
FIGURE 6 CAUSES OF TOOTH DECAY 20
FIGURE 7 ORAL CANCER RELATED FACTS 21
FIGURE 8 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: MARKET STRUCTURE 25
FIGURE 9 RESEARCH PROCESS 26
FIGURE 10 VALUE CHAIN STRUCTURE 32
FIGURE 11 PORTERS FIVE FORCES MODEL OF ARTICAINE HYDROCHLORIDE MARKET 34
FIGURE 12 TERMINAL STERILIZATION PROCESS 36
FIGURE 13 ASEPTIC MANUFACTURING PROCESS 37
FIGURE 14 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY APPLICATION (2015 & 2021) (USD MILLION) 38
FIGURE 15 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR INFILTRATION, BY REGION (2015 & 2021) (USD MILLION) 39
FIGURE 16 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR NERVE BLOCK, BY REGION (2015 & 2021) (USD MILLION) 41
FIGURE 17 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY END USER (2015 & 2021) (USD MILLION) 42
FIGURE 18 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR DENTAL CLINICS, BY REGION (2015 & 2021) (USD MILLION) 43
FIGURE 19 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR HOSPITALS, BY REGION (2015 & 2021) (USD MILLION) 44
FIGURE 20 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: FOR ACADEMIC & RESEARCH INSTITUTES, BY REGION (2015 & 2021) (USD MILLION) 45
FIGURE 21 GLOBAL ARTICAINE HYDROCHLORIDE MARKET, BY REGION, (2015 & 2021) (USD MILLION) 47
FIGURE 22 NORTH AMERICA ARTICAINE HYDROCHLORIDE MARKET, BY COUNTRY, (2015 & 2021) (USD MILLION) 49
FIGURE 23 U.S. LOCAL ANESTHETICS MARKET SHARE, 2015 (%) 53
FIGURE 24 CANADA LOCAL ANESTHETICS MARKET SHARE, 2015 (%) 57
FIGURE 25 EUROPE ARTICAINE HYDROCHLORIDE MARKET, BY REGION, (2015 & 2021) (USD MILLION) 60
FIGURE 26 GERMANY LOCAL ANESTHETICS MARKET SHARE, 2015 (%) 66
FIGURE 27 FRANCE LOCAL ANESTHETICS MARKET SHARE, 2015 (%) 69
FIGURE 28 UK LOCAL ANESTHETICS MARKET SHARE, 2015 (%) 73
FIGURE 29 ASIA PACIFIC ARTICAINE HYDROCHLORIDE MARKET, BY COUNTRY (2011-2016) (USD MILLION) 83
FIGURE 30 AUSTRALIA LOCAL ANESTHETICS MARKET SHARE, 2015 (%) 87
FIGURE 31 MIDDLE EAST AND AFRICA LOCAL ANESTHETICS MARKET SHARE, 2015 (%) 99
FIGURE 32 MIDDLE EAST & AFRICA ARTICAINE HYDROCHLORIDE MARKET, BY COUNTRY (2015 & 2021) (USD MILLION) 100
FIGURE 33 COMPETITIVE ANALYSIS 109
FIGURE 34 GLOBAL ARTICAINE HYDROCHLORIDE MARKET: COMPANY SHARE ANALYSIS, 2015 (%) 112
FIGURE 35 3M: RECENT FINANCIAL 114
FIGURE 36 3M: OPERATING SEGMENTS 114
FIGURE 37 3M: GEOGRAPHIC SEGMENTS 114
FIGURE 38 3M: SWOT ANALYSIS 115
FIGURE 39 ANUHUI BBCA PHARMACEUTICAL CO., LTD.: SWOT ANALYSIS 117
FIGURE 40 DENTSPLY SIRONA: RECENT FINANCIAL 119
FIGURE 41 DENTSPLY SIRONA: OPERATING SEGMENTS 119
FIGURE 42 DENTSPLY SIRONA: GEOGRAPHIC SEGMENTS 119
FIGURE 43 DENTSPLY SIRONA: SWOT ANALYSIS 120
FIGURE 44 INIBSA DENTAL: SWOT ANALYSIS 123
FIGURE 45 JINAN CHENGHUI SHUANGDA CHEMICAL CO. LTD: SWOT ANALYSIS 125
FIGURE 46 JINAN RUIXING PHARMACEUTICAL TECHNOLOGY CO., LTD.: SWOT ANALYSIS 127
FIGURE 47 MANUS AKTTEVA BIOPHARMA: SWOT ANALYSIS 129
FIGURE 48 PFIZER: FINANCIAL REVENUE 131
FIGURE 49 PFIZER: SEGMENTAL REVENUE 131
FIGURE 50 PFIZER: GEOGRAPHIC REVENUE 132
FIGURE 51 PFIZER: SWOT ANALYSIS 133
FIGURE 52 PIERREL S.P.A.: FINANCIAL REVENUE 135
FIGURE 53 PIERREL S.P.A.: SEGMENTAL REVENUE 135
FIGURE 54 PIERREL S.P.A.: SWOT ANALYSIS 136
FIGURE 55 SANOFI: RECENT FINANCIAL 138
FIGURE 56 SANOFI: BUSINESS REVENUE MIX (2015) 138
FIGURE 57 SANOFI: GEOGRAPHIC REVENUE MIX 139
FIGURE 58 SANOFI: SWOT ANALYSIS 140
FIGURE 59 SEPTODONT: SWOT ANALYSIS 142
FIGURE 60 SIEGFRIED AG: FINANCIAL REVENUE 143
FIGURE 61 SIEGFRIED AG: SEGMENT REVENUE 144
FIGURE 62 SIEGFRIED AG: GEOGRAPHIC REVENUE 144
FIGURE 63 SIEGFRIED AG: SWOT ANALYSIS 145
FIGURE 64 SIGMA ALDRICH: FINANCIAL REVENUE 147
FIGURE 65 SIGMA ALDRICH: SEGMENT REVENUE 147
FIGURE 66 SIGMA ALDRICH: GEOGRAPHIC REVENUE 148
FIGURE 67 SIGMA ALDRICH: SWOT ANALYSIS 148
FIGURE 68 MACRO FACTORS IMPACTING ORAL HEALTH 151